John W Glod, MD, PhD

The Cancer Institute of New Jersey (CINJ) 195 Little Albany Street, Room 3551 New Brunswick, NJ 08903 glodjo@umdnj.edu

Clinical Specialty: Pediatric Hematology / Oncology

Degree

• Fellowship from Neuro-oncology Branch NCI
• Fellowship from Johns Hopkins / NCI
• Resident from Children's Hospital Medical Center
• MD, PhD from University of Colorado Health Sciences Center

Grants

• Comparative studies of PDAs and bone marrow-derived MSCs to tumor cells in vitro and in vivo (Celgene (Industry Sponsored Research))
• Role of Macrophages in tumor growth (NJ Commission on Cancer Research )
• The Role of the Bone Marrow Cells in Repair of The Blood Brain Barrier After Injury (NJ Commission on Brain Injury Research)
• The role of Monocytes in Brain Tumor Angiogenesis (Children's Brain Tumor Foundation)

Positions

• Assistant Professor of Pharmacology (01/2007 - Present)
  Pharmacology
  UMDNJ/RWJMS
• Assistant Professor of Pediatric Hematology/Oncology (10/2003 - Present)
  Pediatric Hematology/Oncology
  The Cancer Institute of NJ

Honors

• Medical Honor Society
  University of Colorado, Junior Alpha Omega Alpha (1995)
• Integra Lifesciences Award for Excellence in Pediatric Brain Tumor Research
  Integra LifeSciences Corp. (2006)

Society

• International Society for Stem Cell Research (2008 - Present)
• American Association for Cancer Research (2007 - Present)
• American Society of Pediatric Hematology/Oncology (2004 - Present)
• Children's Oncology Group (2004 - Present)

Publications

• Hui Gao, Waldemar Priebe, John Glod, Debabrata Banerjee. Activation of Signal Transducers and Activators of Transcription 3 and Focal Adhesion Kinase by Stromal Cell-Derived Factor 1 Is Required for Migration of Human Mesenchymal Stem Cells in Response to Tumor Cell-Conditioned Medium. Stem Cells. 20094; 27:857 - 865.
• Anton K, Glod J. Targeting the tumor stroma in cancer therapy. Current Pharmacology Biotechnology. 20092; 10(2):185-91.
• Mishra PJ, Mishra PJ, Glod JW, Banerjee D. Mesenchymal stem cells: flip side of the coin. Cancer Research. 20092; 69(4):1255-8. Cited in PubMed; PMID Epub 2009
• Siang-Yo Lin , Jun Yang, Allen D. Everett, Charles V. Clevenger, Mythili Koneru, Barton Kamen, Debabrata Banerjee, and John Glod (In Press). The isolation of novel mesenchymal stromal cell chemotactic factors from the conditioned medium of tumor cells. Experimental Cell Research. In Press. 2009;
• Ferrari, N, Glod, J*., Lee, J., Kobiler, D., and Fine H.A. Bone Marrow-derived, Endothelial Progenitor-like Cells as Angiogenesis-Selective Gene Targeting Vectors. Gene Therapy. 2003; 10:647-56.
• Anderson, SA, Glod, J, Arbab, AS, Noel, M, Ashari, P, Fine, HA, and Frank, JA., Non-Invasive MR Imaging of Magnetically Labeled Stem Cells to Directly Identify Neovasculature in a Glioma Model. Blood. 2005; 105:420-5.
• Glod, J, Kobiler D, Noel M, Koneru R, Lehrer S, Medina D, Maric D, and Fine HA Monocytes form a vascular barrier and participate in vessel repair after brain injury Blood. 2006; 107:940-46.
• Menon LG, Picinich S, Koneru S, Gao H, Lin SY, Koneru M, Mayer-Kuckuk P, Glod J, and Banerjee D Differential Gene Expression Associated with Migration of Mesenchymal Stem Cells to Conditioned Medium From Tumor Cells or Bone Marrow Cells. Stem Cells. 2007; 25:520-28.
• Cole PD, Drachtman RA, Masterson M, Smith AK, Glod J, Zebala JA, Lisi S, Drapala DA, and Kamen BA. Phase 2B Trial of Aminopterin in Multiagent Therapy for Children with newly Diagnosed Acute Lymphoblastic Leukemia. Cancer Chemotherapy and Pharmacology. 2008; 62:65-75.
• Mishra PJ, Mishra PJ, Humeniuk R, Medina, D, Alexe G, Mesirov JP, Ganesan S, Glod J, and Banerjee D. Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells. Cancer Research. 2008; 68:4331-39.
• Glod, J., Kobiler, D., Noel, M., Maric, D., and Fine, H.A. Monocytes adopt a Brain Microvascular Endothelial Phenotype and Particpate in Vascular Repair after Brain Injury. Blood. 2006; 107(3):940-46.
• Menon LG, Picinich S, Koneru S, Gao H, Lin SY, Koneru M, Mayer-Kuckuk P, Glod J, and Banerjee D Differential Gene Expression Associated with Migration of Mesenchymal Stem Cells to Conditioned Medium From Tumor Cells or Bone Marrow Cells. Stem Cells. 2007; 25:520.
• Jan B. Wollack, Benedette Makori, Stuti Ahlawat, Rajeth Koneru, Sonia Picinich, Angela Smith, I. David Goldman, Andong Qiu, Peter D. Cole, John Glod, and Barton Kamen. Characterization of folate uptake by choroid plexus epithelial cells in a rat primary culture model. J. Neurochem.. 2008; 104:1494.

Research

• Pediatric head and neck cancers